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This study established the core evidence that drives current research interest and it is important to note that this is primarily a preclinical (mouse) evidence base

This is part of why B12 has a strong safety record, and it is also why levels sometimes need regular replenishment during active treatment

In fact, oral supplementation is just as effective and carries the added benefi ts of lower cost and ease of administration.*[2,3]

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J Paediatr Child Health 2013;49:820-4

However, scientific evidence does not show that these injections directly promote weight loss in healthy individuals who are not B12 deficient